Comparative study of serum and synovial fluid monokine levels in patients with juvenile spondyloarthropathies and their clinical significance
- VernacularTitle:血清及关节液中单核因子表达水平的测定及其在幼年脊柱关节病中的临床意义
- Author:
Wei ZHAO
;
Feng HUANG
;
Ming XU
- Publication Type:Journal Article
- Keywords:
Monokines;
Pathology,clinical;
Spondyloarthropathies,juvenile
- From:
Chinese Journal of Rheumatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the monokine levels of serum and synovial fluid (SF) in patients with JSpAs and estimate the correlation between monokines and inflammatory indices.Methods Serum and SF monokines (IL 1?,IL 1?,IL 6,IL 8,IL 12 and TNF ?) were measured by sandwich ELISA in patients with JSpAs ( n =28) and healthy controls ( n =10).The correlation between serum monokines and inflammatory indeces and between both serum and SF monokine levels was analysed.Results Elevated serum level of IL 6 was found in patients with JSpAs as compared to healthy controls ( P
