Effects of injecting the colloidal chromic phosphate ~(32)P into articular cavity on arthritis in rats
- VernacularTitle:胶体磷酸铬~(32)P关节腔内注射对大鼠关节炎模型的影响
- Author:
Feng DING
;
Xingfu LI
;
Tingguo ZHANG
- Publication Type:Journal Article
- Keywords:
Arthritis;
Rats,Spraque Dawley;
Colloidal chromic phosphate 32 P;
Injection,intrasynovial
- From:
Chinese Journal of Rheumatology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficiency of injection of colloidal chromic phosphate 32 P cavity in rats with rheumatoid arthritis.Methods Collagen induced arthritis (CIA) was produced in Sprague Dawley rats.After one week immune,the right post ankle was given colloidal chromic phosphate 32 P intra articular injection.Severity of arthritis was observed by the left to right diameter of the right post ankle joint,the volume of right post paw and the arthritic index.Results The group treated with colloidal chromic phosphate 32 P intra articular injection developed milder arthritis compared with control CIA group after 6 weeks.The left to right diameter of the right post ankle joint was (3 96?0 05) mm of the colloidal chromic phosphate 32 P intra articular treated group compared with (4 11?0 08) mm of the control CIA group ( P
