Clinical significance of liver biopsy for chronic hepatitis B with persistently normal transaminases
- VernacularTitle:肝活检对转氨酶正常的慢性乙型肝炎感染的临床意义
- Author:
Liuming YANG
;
Kecheng XU
;
Yanlong ZHAO
- Publication Type:Journal Article
- Keywords:
Hepatits B virus infection;
Chronic hepatits B;
Liver biopsy;
Hepatic histology
- From:
Chinese Journal of Digestion
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective The histological features of chronic hepatitis B virus (HBV) infection with persistently normal serum transaminases has not been will studied. The aim of this study was to investigate clinical significance of liver biopsy for these patients. Methods A total of 452 HBsAg positive patients and clinical course of more than six months undergone percutaneous liver biopsy. All liver biopsy specimens were assessed by experienced liver pathologists blinded to the liver biochemistry and scored according to standard criteria. Results None of patients had normal liver pathology. Patients with elevated serum transaminases had significant higher degree of hepatic necrosis inflammation grade (G) and fibrosis stage (S) compared with pateitns with normal transaminase ( P
