Application of the Solvent Systems Software of High-speed Countercurrent Chromatography in Studying the Active Fraction A of Guizhi Decoction
- VernacularTitle:高速逆流色谱溶剂体系软件在桂枝汤A部分研究中的应用
- Author:
Deshun DAI
;
Yiming WANG
;
Guoan LUO
- Publication Type:Journal Article
- Keywords:
high-speed countercurrent chromatography;
solvent systems software;
TCM;
Guizhi-decoction
- From:
Chinese Traditional Patent Medicine
1992;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To introduce a new way, which facilitates the systematic search and evaluation of the solvent systems suitable for high-speed countercurrent chromatography (HSCCC). Methods: The software integrated with the thermodynamics solution functions and theory is directive to calculate the composition, physical parameters, such as volume, viscosity, dielectric constants, and polarity parameters of the upper and lower phases. Results: Separation of Guizhi-decoction Fr. A by HSCCC, one of traditional Chinese medcines, is conducted to prove the applicability of this software in selection and optimization of solvent systems. Conclusion: This software can be used to select and optimize the solvent systems of HSCCC. It is supposed to extend this method.
