Three routes for interventional chemotherapy in the treatment of NSCLC later lung cancer
- VernacularTitle:三种化疗方法治疗中晚期非小细胞肺癌的临床回顾性分析
- Author:
Congjing GAO
;
Nanzheng ZHANG
;
Yue SHI
- Publication Type:Journal Article
- Keywords:
Ways of drug administration;
Non small cell lung cancer;
Follow up
- From:
Journal of Interventional Radiology
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the treating of 443 NSCLC cases in the middle and late stages. Three ways of drug administration had been reported as follows: intravenous drop (IVD) 301 cases, bronchial artery infusion (BAI) 64 cases, bronchial and pulmonary arteres for dual infusin (DAI) 78 cases. Methods From 1980 on 97th Hospital of PLA had already treated 443 cases of NSCLE of advance lung cancer. Three ways of drug administration had been analyzed. Results The recent effective rates attained as 53.0%, 73.4% and 98.7% with mean survival rates of 7.3、10.8 and 12.4 months respectively for the 3 groups. Conclusion The authors consider that the combination of MFP or EAP and CAMB is a better plan to treat NSCLC. The high concentration of chemical drugs directly act on the local tumor by applying BAI with high shrinking rate of tumor and increased resection rate. Because of double blood supply of lung by bronchial and pulmonary arteries, DAI will correct certain defects of BAI to increase therapeutic effect as well as reduce and avoid certain side effects of BAI.