Telomerase activity in cervical cancer and its precursor lesion
- VernacularTitle:子宫颈癌及其癌前病变组织端粒酶活性的研究
- Author:
Yuhuan QIAO
;
Mengzhen ZHANG
;
Huirong SHI
- Publication Type:Journal Article
- Keywords:
Cervix neoplasms;
Telomerase;
Cervical intraepithelial neoplasia
- From:
Chinese Journal of Obstetrics and Gynecology
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study telomerase activity in cervical cancer and it′s precursor lesion Methods Thirty six cervical cancer and 16 cervical intraepithelial neoplasia (CIN) specimens were measured for telomerase activity using TRAP ELISA, and 11 normal cervix, 6 chronic cervicitis and 8 adjacent normal tissue specimens as controls Results Mean telomerase activity in CIN, cervical cancer, and controls were 0 398?0 293, 1 580?0 819, 0 050?0 012 There was statistically significant difference among three groups ( P
