Molecular marker makes tailored target therapy for mCRC treatment
- VernacularTitle:转移性结直肠癌靶向治疗个体化选择
- Author:
Lin SHEN
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Neoplasm metastasis;
Targeted therapy
- From:
Cancer Research and Clinic
2008;20(8):507-508,512
- CountryChina
- Language:Chinese
-
Abstract:
The latest advances on target therapies of cancer were presented on the 44th Annual Meeting of American Society of Clinical Oncology(ASCO)in 2008.One of the most important results was the outstanding efficacy of Cetuximab in Metastatic Colorectal Cancer fIncao patients with k-ras"wild-type".Besides,detection of k-ras statuswouldmakeitpossibleforthetailoredtargettherapy of mCRC.Itwasestimatedthat k-ras gene status would become a predictive molecular marker for Cetuximab treatment in mCRC.