The role of Sertoli cells in the testes spermatogenesis and its damage in the radiation
- VernacularTitle:睾丸Sertoli细胞在精子发生中的作用及辐射损伤
- Author:
Yanmei WANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(18):-
- CountryChina
- Language:Chinese
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Abstract:
A Sertoli cell resides in testicular seminiferous tubule,which is the only body cell contact with the spermatogenic cell,plays a crucial role of regulation in the process of spermatogenesis.Sertoli cells can provide a material basis and a favorable microenvironment for sperm.After X radiation,spermatogenic cells and mitochondrion dramatically swelling and lysis with a decrease of mitochondrial cristae,with the prolonging of time,the mitochondria damage get even worse,mitochondrial crista is disappeared.The results of the current study indicate that radiation can cause Sertoli cell damage,but the complete theoretical system remains unclear,which needs combines with other subjects for further study.
