Expression of cystatin B gene in human esophageal cancer
- VernacularTitle:cystatin B基因在人食管癌中的表达
- Author:
Changqing GUO
;
Mingrong WANG
;
Jichang LI
- Publication Type:Journal Article
- Keywords:
cystatin B gene;
Esophageal neoplasms;
Gene expression;
Reverse transcript polymerase chain reaction;
Neoplasm metastasis
- From:
Chinese Journal of Digestion
1998;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the status of cystatin B gene expression in human esophageal cancer. Methods Expression of cystatin B gene was detected by RT PCR in 41 pairs of human esophageal cancer tissues, matched adjacent normal mucosa, human esophageal cancer cell line EC9706 and human lung cancer cell line GLC82. Results cystatin B gene expression was down regulated in 82.9% (34/41) of human esophageal cancer tissues while expressed at high level in all matched adjacent normal esophageal mucosa, and was significantly corelated to lymph node metastasis ( P
