A Pharmacodynamic Study of Penyan Qing Capsule
- VernacularTitle:盆炎清胶囊主要药效学研究
- Author:
Biqiong SHEN
;
Yi SITU
;
Yongquan OU
- Publication Type:Journal Article
- Keywords:
PENYAN QING CAPSULE/pharmacology;
CHRONIC PELVIC INFLAMMATION/TCD therapy;
ADNEXITIS/TCD therapy;
SALVIA MILTIORRHIZA/ther. use;
RADIX PAEONIAE RUBRA/ther.use
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the main pharmacological actions of Penyan Qing Capsule (PQC) for chronic pelvic inflammation. Methods The analgesic action of PQC was studied by mouse hot_plate method. Experiments of mouse auricular swell ing and rat agar_induced granuloma were carried out to investigate the anti_infl ammatory action of PQC. Effects of PQC on function of mouse mononuclear phagocyt es and rat mesenteric microcirculation were also studied. Results PQC increa sed the rat pain threshold, reduced mouse auricular swelling induced by xylene a nd the weight of rat agar_induced granuloma. PQC could also improved rat mesente ric microcirculation disorder induced by noradrenline and increase the function of mouse mononuclear phagocytes. Conclusion PQC exerts good anti_inflammatory and analagisic action and can improve microcirculation. This will supply pharm acodynamic evidence for the application of PQC in clinic.
