Detection of transfusion transmitted virus infection and genotypes in pregnant women
- VernacularTitle:孕妇血清及乳汁中输血传播病毒DNA及其基因型检测的研究
- Author:
Zhi ZHANG
;
Zhen ZHANG
- Publication Type:Journal Article
- Keywords:
DNA viruses;
Pregnancy;
Polymerase chain reaction;
Genotype
- From:
Chinese Journal of Obstetrics and Gynecology
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To clarify the frequency, the routes of transmission from mother to infant, the correlation factors and distribution of genotypes of transfusion transmitted virus (TTV) infection. Methods Nested polymerase chain reaction (n PCR) was performed to detect TTV DNA and genotypes in serums and breast milks from 160 cases of pregnant women. Results TTV DNA in serum and breast milk was detected in 64 (40 0%) and 60 (37 5%) of 160 cases of pregnant women respectively. The positive rates of TTV DNA from HBV markers (+) and normal groups were 50 0%, 43 1% and 13 6%, 22 7% respectively in serums and breast milk. There were significant difference between the two groups ( P
