Effect of Ruanmai Capsule on Cerebral Ischemia-reperfusion Injury in Rats
- VernacularTitle:软脉胶囊对脑缺血再灌注大鼠的影响
- Author:
Wei LI
;
Shuxiao TIAN
- Publication Type:Journal Article
- Keywords:
Ruanmai Capsule;
cerebral ischemia-reperfusion
- From:
Chinese Traditional Patent Medicine
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the protective effects of Ruanmai Capsules on cerebral ischemia-reperfuse injury in rats.Methods:A cerebral ischemia-reperfuse model in rats was established by ligaturing bilateral arterial carotis communis and vagus nerve. NO, 6-keto-PGF 1a and TXB 2 in serum were examined. Results: Ruanmai Capsule (0.81g/kg and 2.43g/kg,po) increased the levels of NO, 6-keto-PGF 1a. It also had the tendency to decrease TXB 2 in serum. Conclusions: Ruanmai capsules can alleviate brain injury caused by cerebral ischemia reperfusion. The effect is achieved perhaps by inhibiting platelet aggregation and increasing NO.
