Determination of Paracetamol and Caffeine in New compound Folium Isatidis Tablets by HPLC
- VernacularTitle:HPLC测定新复方大青叶片中扑热息痛和咖啡因的含量
- Author:
Shanxue JIA
;
Yupeng GUO
;
Baorong SHI
;
Junhua ZHANG
;
Wei ZHAO
- Publication Type:Journal Article
- Keywords:
HPLC;
New Compound Folium Isatidis Tablets;
paracetamol;
caffeine
- From:
Chinese Traditional Patent Medicine
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To determine the contents of paraceltamol and caffeine in New compouad Folium Isatidis Tablets simultaneously by HPLC. Methods:The determination was carried out with C 18 chemical bonded silica gel as a solid phase, methanol-water (25∶75) as a mobile phase and UV deterction wavelength at 215 nm. Results: The average recovenies of the added sample were 99.6%( RSD=0.67, n=5) for paracetamol and 99.3%(RSD=0.58, n=5) for caffine, There was a good linear relationship between the concentration and absorption area value in the rang of 1.6?g～6.4?g for paractamol or 0.16?g～0.64?g for caffeine.Conclusions: The method is simple, quick and accurate.
