Antidepressants in the treatment of functional dyspepsia
- VernacularTitle:联合抗抑郁药治疗功能性消化不良的临床研究
- Author:
Bihui YANG
;
Yongping ZHENG
;
Zhensong GAO
- Publication Type:Journal Article
- Keywords:
Functional dyspepsia;
Depression;
Antidepressants
- From:
Chinese Journal of Digestion
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of antidepressants in the treatment of functional dyspepsia (FD). Methods 90 cases of FD with anxious depressive manifestations were randomizely allocated into antidyspepsia group, antidepressant group and antidyspepsia and antidepressants combination group. All patients were treated for 8 weeks. Results FD scores(upper abdominal distention, satiety, abdominal pain, belching) with Zung depression scale and HAMD scale decreased after treatment in all three groups. Symptoms in combination group improved with a total efficacy rate of 86.7%, and HAMD efficacy rate 86.7%. Both were much higher than those in antidyspepsia group(36.7% and 10.0%, respectively, P
