Influences of Chuan Shen Tong Injection on Epidermal Growth Factor and Its Receptor in Human Benign Prostatic Hyperplasia
- VernacularTitle:川参通注射液对前列腺增生组织中表皮生长因子及其受体表达的影响
- Author:
Licheng JIANG
;
Hong PAN
;
Naixu MA
- Publication Type:Journal Article
- Keywords:
Chuan Shen Tong Injection/therapeutic use;
Prostatic hyperplasia/TCD therapy;
@epidermal growth factor (EGF)/drug effect;
@epidermal growth factor receptor(EGFR)/ drug effect
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the mechanism of Chuan Shen Tong Injection (CSTI) for benign prostatic hyperplasia (BPH).Methods:The distribution of epidermal growth factor (EGF) and epidermal growth factor receptor(EGFR) expression were detected with immunohistochemical technique in 49 samples of the excised prostate. Among them, 18 samples were from patients without intraglandular injection of CSTI (group A) as controls, 21 from those receiving injection but without effect (group B) and 10 from those receiving injection with effect but recur (group C).Results: The positive expression rates of interstitial EGF and EGFR in group B (81% and 71.4% respectively) increased as compared with group A (33.3% and 33.3% respectively.,P
