Effect of Borneolum on Expression of ICAM-1 in Microvascular endothelial Cells of Rat Brain
- VernacularTitle:冰片对大鼠脑微血管内皮细胞ICAM-1表达量的影响
- Author:
Baosheng ZHAO
;
Suiqing MI
- Publication Type:Journal Article
- Keywords:
Borneolum/pharmacology;
Blood-brain barrier/drug effect;
@ICAM-1/ drug effect
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Methods: The experimental brain injury was induced in the SD rats by free falling object, and the expression of intercelluar adhesion molecule-1(ICAM-1)in the microvascular endothelial cells (EC) of rat brain was examined by immunohistochemistry and S-P histochemical methods.The rats were allocated to group A(normal blank control group), group B (administration of Borneolum), group C(brain injured model group) and group D(model rats treated with Borneolum).Results:ICAM-1 seldom expressed or never expressed in the normal rats brain,the administration of Borneolum could not induce its expression,and ICAM-1 expression increased in the injured brain(P
