Anti-inflammatory, Analgesic and Immunosuppressive Action of Niuhuang Qianjin San
- VernacularTitle:牛黄千金散抗炎镇痛和免疫抑制作用
- Author:
Qingrong XU
;
Na LI
;
Guanhua DU
- Publication Type:Journal Article
- Keywords:
Niuhuang Qianjin San (NQS)/pharmacology;
@ Analagisic and immunosuppressive action;
Immunosuppression;
Rats;
Mice
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the anti-inflammatory, analgesic and immunosuppressive action of Niuhuang Qianjin San (NQS). Methods: The anti-inflammatory action of NQS was studied by the methods of rat paw swelling and mouse ear swelling and the analgesic action by mouse body torsion method and K + subcutaneous penetration method in rats.Immunosuppressive effect was evaluated by peripheral T lymphocyte percentage, splenic lymphocyte transformation ratio, phagocytic function of intraperitoneal magocytes, the activity of delayed hypersensitivity, serum hemolysin level and the function of antibody-yielding cells in mice. Results: NQS could obviously alleviate inflammation, increase codeine's analgesic action and suppress immunity. The difference were significant (P
