Oxygen Free Radical Clearing Activity and Anti-lipid Peroxidation of Shengyaling Injection in Vitro
- VernacularTitle:升压灵注射液清除氧自由基和抗脂质过氧化作用
- Author:
Lingdong KONG
;
Yaolin WEN
;
Huipin WU
- Publication Type:Journal Article
- Keywords:
Shengyaling injection/pharmalogy;
shock/TCD therapy
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe oxygen-free-radical clearing activity and anti-lipid peroxidation of Shengyaling injection in vitro. Method: In-vitro oxygen free radical generation system (OFRGS) and lipid peroxidation induced by OFRGS in the supernatant fluid of mice heart tissue homogenate were used to evaluate the anti-oxidation activity of Shengyaling injection. Result:Shengyaling injection cleared superoxidase anion free radical induced by hypoxanthine-xanthine oxidase system and hydroxyl free radical induced by fenton reaction system, and inhibited mice heart tissue lipid peroxidation induced by FRGS at a dose-dependent manner. Conclusion:Shengyaling injection possesses an anti-oxidation effect.
