DOUBLE MINUTES EXPRESSION AND ITS SIGNIFICANCE IN PREOPERATIVE AND POSTOPERATIVE PATIENTS WITH BLADDER TRANSITIOAL CELL CARCINOMA
- VernacularTitle:膀胱移行上皮细胞癌患者手术前后外周血双微体的表达意义
- Author:
Xiaotong HU
;
Weizhen XU
;
Wenxiang GU
- Publication Type:Journal Article
- Keywords:
Bladder transitional cell carcinoma;
Double minutes;
Prognosis
- From:
Acta Anatomica Sinica
1989;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of double minutes (DM) in bladder transitional cell carcinoma (TCC) and its significance. Methods 15 control individuals and 14 patients were examined. Whole blood samples from these patients were cultured before and 10-15 days after operations. The relationship between expression of DM and clinic-pathologic factors and prognosis was ana- lyzed by chi-square test. Results There is no DM in control individuals, but there are respectively 35 pairs and 31 pairs DM in preop- erative and optoperative patients with TCC (P 0. 05). Conclusions DM may be an independent prognosis indication of cancer gene amplication. DM always show treatment failure and rapid recurrence.
