Comparison of Dissolution Rates in vitro of Maxingshigan Dropping Pill and Suppository
- VernacularTitle:麻杏石甘滴丸与栓剂体外溶出度比较
- Author:
Qun HE
;
Rong ZENG
;
Li WANG
;
You HUANG
- Publication Type:Journal Article
- Keywords:
Maxingshigan Dropping pill;
Maxingshigan Suppository;
dissolution rate in vitro;
rotary basket method;
Ephedra alkaloid;
acidic dye colorimetry
- From:
Chinese Traditional Patent Medicine
1992;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explorate the drug releasing rule in vitro of Maxingshigan Dropping pill and Suppository. Methods: Their dissolution rates in vitro were determined by the rotary basket method, the contents of total alkaloid in ephedra alkaloid in the two preparations were determined by acidic dye colorimetry, and they were used as markers of dissolution.Results:The dissolution quantity in 45 min of Dropping pill reached 100%, whereas that of suppository reached 92.58%. Conclusion: T 50 , T d of the two preparations showed significant difference ( P
