Effect of Xiao Chaihu Decoction on the Release of NO from Mouse Peritoneal Microphage in Vitro
- VernacularTitle:小柴胡汤对小鼠腹腔巨噬细胞释放NO的影响
- Author:
Yao XU
;
Guowu BIAN
;
Minyu WU
- Publication Type:Journal Article
- Keywords:
Xiao Chaihu Tang/pharmacol.;
macrophophages/drug eff.;
nitric oxide;
@Serologic pharmacology
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
To explore the antihepatotoxic mechanism of alcohol_extract of Xiao Chaihu Decoction (XCD),Giress reagent was used to observe the effect of the sero_alcohol_extract of XCD and alcohol_extract of XCD on the release of NO from mouse peritoneal macrophage in vitro.The results showed that alcohol_extract of XCD had no effect on the release of NO while the production of NO was improved in the cultured peritoneal macrophage after the medication of sero_alcohol_extract of XCD for 120min,180min and 240min.It is indicated that improving the release of NO from macrophage was one of the mechanisms of XCD in counteracting hepatic damage.
