A Preliminary Study on the Establishment of Animal Model with Hyperuricemia
- VernacularTitle:高尿酸血症动物模型初探
- Author:
Can TANG
;
Kui YANG
- Publication Type:Journal Article
- Keywords:
Hyperuricemia;
animal desease models;
hypoxanthine
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Hypoxanthine,the pre_substance of uric acid,was used to create mouse model with hyperuricemia.The dose_effect relationship and time_effect relationship of hypoxanthine during the model establishment were observed.The effect of sex and xanthine oxidase inhibitor on the establishment of mouse model was studied.The results showed this method is effective for the establishment of a stable mouse model with hyperuricemia.
