Effects of Xiangsha Liujunzi Decoction on Experimental Bile-Regurgitational Gastritis in Rats
- VernacularTitle:香砂六君子汤对实验性胆汁返流性胃炎的治疗作用
- Author:
Minghong HAO
;
Weimin ZHAI
- Publication Type:Journal Article
- Keywords:
@Xiangsha Liujunzi Decoction /pharmacology;
@bile-regurgitational gastritis / therapy , TCM;
Gastric mucosa /secretion Gastric emptying /drug effects
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The effects of Xiangsha Liujunzi Decoction (XLD) on expermental bile-regurgitational gastritis and gastric evacuation in rats were observed. XLD in dose of 30g/kg (p.o.) markedly pre- vented the acute gastric ucosa damate induced by gastric feeding of alkaline intestinal contents. For chronic regurgitational gastritis rat model induced by pyloric dilation with regurgitation of duodenal juice after 2 and 4 weeks , XLD in dose of 30g/kg (p. o.) lowered the incidence of gastritis, and reduce intragastric pH and bile acid. XLD in dose of 15g/kg and 30g/kg (p.o.) markedly inhibited the gastric evacuation. The results suggested that XLD is available for the treament of bile-regurgi- tational gastritis.
