CHANGES OF c  fos GENE IN PERIAQUEDUCTAL GRAY OF AUDIOGENIC SEIZURES  PRONE RATS FOLLOWING AUDIOGENIC SEIZURES

VernacularTitle:听源性惊厥发作后中脑导水管周围灰质内c-fos基因的变化
Author: Meng LIU ; Luxi XU
Publication Type:Journal Article
Keywords: Periaqueductal gray; Fos; Audiogenic seizures; Rats
From: Acta Anatomica Sinica 1955;0(03):-
CountryChina
Language:Chinese
Abstract: Objective\ To find out the relationship between the periaqueductal gray (PAG) and the audiogenic seizures. Methods The neuronal(Nissl)staining method and the immunocytochemical method were used to identify the Fos postive neurons in the PAG of the audiogenic seizures prone rats(P77PMC) after audiogenic seizures. Results There were lots of Fos positive neurons in the dorsolateral, dorsal and caudoventrolateral subdivisions of the PAG in P77PMC rats two hours post seizure, and the percentage of Fos positive neurons was significant higher than that of rats in control groups. Conclusion A large number of neurons in the PAG of the audiogenic seizures prone rats participated in the process of the audiogenic seizures.