Effect of Kebimin Spray on Substan on Substance P Contents in Lung and Plasma of Guinea Pigs with Hhypersensitive Rhinitis
- VernacularTitle:中药克鼻敏喷剂对超敏性鼻炎豚鼠血浆、肺中P物质的影响
- Author:
Yanfang QIAN
;
Bingwen LI
;
Zhengmou ZHOU
;
Yanyan BAO
;
Jinrang LI
- Publication Type:Journal Article
- Keywords:
＠KEBIMIN SPRAY/pharmacol.;
RHINITIS, ALLERGIC, PERENNIAL/TCD ther.;
ADMINISTRATION,INTRANASAL;
SUBSTANCE P/blood
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the antisensitiZation of Chinese drug, Inodel gUinea pigS with hypersensitive thinilistabbed with Kebindn Sray Served as Group l, and substance P(SP) contents in lung and plasma ofGroup I were detected and compared with normal coned group (Group 11),model control groUp(Group ill) and poSitive medicine control group(GrouP ac).The resultS showed that SP content inlung and plasma of Group ill were higher than thais of GrouP 11(P 0.05).SP is an active neuropeptide and over release of SP Inay result in hperetion of the nose.It is indicated that Kebimin SPlaycan inhibit type I alleds by decreasing SP contents in lung and plasma.
