nm23 gene product/NDPK expression in gastric carcinoma and its prognostic significance
- VernacularTitle:nm23基因产物/NDPK在胃癌中的表达及其预后意义
- Author:
Chuan WANG
;
Xiangfu ZHANG
;
Faduan YANG
- Publication Type:Journal Article
- Keywords:
Gene,inhibition Stomach neoplasm Nucleoside diphophate kinase
- From:
Chinese Journal of Digestion
1996;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
The expression of nm23 gene product/NDPK was studied in curatively resected human gastric carcinoma, using anti-NDPK polyclonal antibody. Of 115 patients tested, 59.1%(68/115) showed positive staining in the primary lesions, and 41.9%(36/86) were positive in the metastatic regional lymph nodes. A significantly higher positive staining rate was found in patients without regional nodal metastasis (86.2%, 25/29) than in those with nodal involvement (50.0%, 43/86; P