Effects of Alcohol Extract of White-flower Hogfennel(Peucedanum praeruptorum) on Left Ventricular Hypertrophied Hypertensive Rats
- VernacularTitle:白花前胡浸膏对肾型高血压大鼠左室肥厚的预防作用
- Author:
Yong JI
;
Manren RAO
- Publication Type:Journal Article
- From:
Chinese Traditional and Herbal Drugs
1994;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
In left ventricular hypertrophied hypertensive rats (LVH), effects of alcohol extract of Peucedanum praeruptorum(QHJG)on left ventricular(LV)compliance and Ca2+content in left ventricular myocardial mito chondria and tail artery were studied.QHJG 0.6g/100g(body weight).d was given for 9 weeks (ig). The LV compliance in LVH group was significantly decreased as compared with that in the sham-operated group. The Ca2+ content in left ventricular myocardial mitochondria and tail artery of LVH group was markedly raised. But QHJG could mardedly im prove the LV compliance and decrease the Ca2+ of left ventricular myocardial mitochondria and tissues of tail artery from LVH rats.These results suggest that QHJG can improve the LV compliance in LVH rats,which maybe related to its reduction of Ca2+ content of LV myocardial mitochondria and tissues of tail artery
