Hemodynamic Effects of Laigechongji(LGCJ)on Anesthetized Open-Chest Dog
- VernacularTitle:莱葛冲剂对麻醉开胸犬血流动力学的作用
- Author:
Dayan SUI
;
Zhongzhi LU
;
Xiaofen YU
- Publication Type:Journal Article
- From:
Chinese Traditional and Herbal Drugs
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Hemodynamic effects of Laigechongji (LGCJ)were studied in anesthetized open-chest dogs. LGCJ(in doseof 8. 5 and 17.0g/kg,id. )decreased significantly SBP, DBP, MAP, HR, LVSP, +dp/dt max and TPVR, 30~45 mins after medication,and continued for about 90~ 150mins. However,they had no significant effects ondp/dt max,LVEDP,CO,CI,SV and SI. These results suggest that LGCJ may cause hypotension,and its hypotensive effects may be related to its bradycardiac,negative inotropic and vascular resistance reducing activities.
