Beneficial Effect of Linaoxin Capsule on Experimental Cerebral Infarction in Rats and Brain Energy Metabolism in Cerebral Ischemic Mice
- VernacularTitle:利脑心胶囊对大鼠实验性脑梗塞及小鼠脑缺血后能量代谢的改善作用
- Author:
Qingyu ZHOTL
;
Weiren XU
;
Yuefang WEI
- Publication Type:Journal Article
- From:
Chinese Traditional and Herbal Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Linaoxin, a herhal preparatlon composed of Salvia miiltiorrhiza, Ligusticum wallichii,Pueraria lobata,and Polygonum multiflorum etc., at doses of O. 25 and o. 5g/kg (ig)significantly improved the neural symptoms of experimental cerehral infarction and reduced the size of infarcted area in rats. At the same doses it also significantly prolonged the hreathing time of mice after decapitation and showed effects on brain energyrnetabolism including the increase of brain ATP and phosphocreatine (Pcr)leveIs and decrease of brain lacticacid (LA)level. Linaoxin suspension at concentrations of l:
