Studies on Hemostatic Activity and Pharmacology of Shenxueling
- VernacularTitle:生血灵的止血作用和药理研究
- Author:
Yongming ZHOU
;
Yikui LI
- Publication Type:Journal Article
- From:
Chinese Traditional and Herbal Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Pharmacology of Shpnxueling(SXL),a traditional Chinese medicine used for the treatment of idiopathicthrombocytopenic purpura,and its hemostatic activity were studied in experimental animals. Results showedthat SXL shortened the time of bleeding and coagulation,raised BPC in mice,increased platelet megakaryocyteproduction in rabbit,prolong the time of swiming of 1oaded mice,increased body liver and kidney weights ofyoung mice, increased p1asma cortisol Ievel. Acute and chronic toxicity tests reveaIed that SXL was nontoxicto mice or rats. These results suggested that hemostasis was associated with effects of SXl, which could faci1i-tate division and maturity of megakaryocyte,increase the BPC,accelerate coagulation and regulate the functionof endocrine. SXL could resist fatigue,endure hypoxia,faciIitate growth. lt is safe and nontoxic in its use of'SXL.