In Vitro Dissolution Test of Flavonoid Pilulae from Gegen
- VernacularTitle:葛根黄酮滴丸体外释放度的研究
- Author:
Jianping GUO
;
Tongying ZHAO
- Publication Type:Journal Article
- From:
Chinese Traditional and Herbal Drugs
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Flavonoid Pilulae from Gegen were prepared by melting method. Using PEG 4000 and PEG 6000 as carrier. Serious of studies on the in yitro release kinetics were carried out.PEG4000 ; PEG6000 ratio had no effect on the release kinetics. PEG 4000: flavonoids ratio had an evident effect on the release properties of the pilulae, the higher the ratio,the faster the release rate. But when the PEG 4000, flavonoids ratio exceeded 10: 1, a reverse effect could be seen. Compared with "Gegen flavonoids" tablets, "Yufengingxin" tablets(release half time, T50= 94.79min), the pilulae gave a much fast release characteristic (T50 = 11. 56min).
