Studies on the Pharmacology of Extracts of Tianshan Mountain Mountainash (Sorbus tianschanica )
- VernacularTitle:天山花楸水提取液药理学研究
- Author:
Dimin LI
;
Jian CHEN
- Publication Type:Journal Article
- From:
Chinese Traditional and Herbal Drugs
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
It has got good effects that aqueous extracts of Sorbus tianschonica Rupr (AQ-ESTR) used for the treatment of chronic bronchitis, Pulmonary tuberculosis and edema etc in folk medicine. The pharmacological experiment showed that AQESTR had antibechic effect on mice induced by ammonia water, expectorant effect and antiasthmic effect on guinea pig induced by mixture of Ach-histamine. Cardiac Pharmacological experiment also showed AQESTR Produced significant bridycardia in mice. At the dose of 25mg/kg, AQESTR decreascd the heart rate and Prolonged the P-r interval of ECG in vivo, AQESTR decreased the contractive force of isolated atrial muscles rabbits in dose-dependent manner.