Effect of Extract Zhonghuabie (Amyda sinensis ) on Syntheses of DNA and Protein in Mice
- VernacularTitle:鳖制剂对小鼠核酸蛋白质合成的影响
- Author:
Tiangui HUANG
;
Zhuliang TAO
- Publication Type:Journal Article
- From:
Chinese Traditional and Herbal Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Extract Amyda sinensis raised the levels of Plasma proteins. Plasma albumin was raised from 2.67?0.44 to 3.25?0.34g/dl and the total Plasma protein from 5.34?0.88 to 6. 74 ?1. 38 /dl. 3H-TdR and .3H-Leucine incorporation techniques were used to measure the syntheses rate of DAN and protein .The rates was accelerated.The specifie activities of DNA and protein of liver got up to 3.90?1.41 from 2.42?0.71 dpm/?g, and 21.69?4.84 from 12.81 ?5.83 dpm/?g, respectively.Those of spleen got up to 41.88?18.47 from 19.04?10.54 dpm/?g and 23.12?4.38 from 16.34?7.01 d pm/?g, respectively. Extract Amyda sinensis had no effect on DNA synthesis of bone marrow cells and did not raise the hemoglobin level in mice. The results suggest that Extract Amyda sinensis has bioactive substance that accelcrate synthcses of DNA and protein.
