Prediction of the Need for Mechanical Ventilation following Thymectomy in Myasthenia Gravis.
10.4097/kjae.1992.25.4.740
- Author:
Kyeong Tae MIN
1
;
Mi Young CHOI
;
Jong Rae KIM
Author Information
1. Department of Anesthesiology, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Complication;
myasthenia gravis;
surgey;
thymectomy;
ventilation;
mechanical
- MeSH:
Anesthesia, Inhalation;
Humans;
Myasthenia Gravis*;
Pyridostigmine Bromide;
Respiration, Artificial*;
Retrospective Studies;
Risk Factors;
Thymectomy*;
Ventilation;
Vital Capacity
- From:Korean Journal of Anesthesiology
1992;25(4):740-744
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Leventhal, et al. described a preoperative scoring system for myasthenic patients undergoing transsternal thymectomy, which includes four key risk factors. There were : 1) duration of myasthenia gravis greater than 6 years (12 points); 2) a history of chronic respiratory disease not due to myasthenia gravis(10 points); 3) a dose of pyridostigmine greater than 750mg per day 48 hours before operation (8 points); 4) a preoperative vital capacity less than 2.9L(4 points). Thirty-seven patients with myasthenia gravis undergoing transsternal thymectomy under general inhalation anesthesia with or without muscle relaxants were applied to scoring system by leventhal, et al. retrospectively. The predicitive score was assessed for each patient and the duration of postoperative mechanical ventilation was also noted for each patient. in this study, there was correct in 23/37(62.2%) of the cases, with 9 out of 27 being incorrectly predicted to be ready for tracheal extubation(false positive) and 5 out of 10 being incorrectly predicted to need ventilation(false positve). In conclusion, the scoring system proposed by leventhal, et al. may be some value in predicting whether or not a particular myasthenic patient was likely to need mechanical ventilation following transsternal thymectomy.
