Experimental Studies on the Effect of“Liver-Softening Anti-Fibrotic Decoction”on Active and Inactive Fibrotic Rats
- VernacularTitle:柔肝抗纤方对活动性和非活动性肝纤维化大鼠作用的实验研究
- Author:
Shugen JING
;
Lingtai WANG
;
Jiawei REN
- Publication Type:Journal Article
- From:
Chinese Traditional and Herbal Drugs
1994;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Liver-Softening Anti-Fibrotic Decoction", a preparation consisted mainly of medicinal qerbs with touifying "Qi", flourishing"Yin", activating blood and eliminating stasis, was given by gavage to Dimethyl nitrosamine (DMN) induced fibrotic rat to assess its effect on ative and inactive liver fibrosis. It was found that this preparation, besides its promoting growth aud protein metabolism activeties, can also lower serum alkaline phosphatase, decrease serum hyaluronate and liver hydroxy proline, with a better curative effect on experimental liver fibrosis in rats than its prophylactic effect