On the Effect of Total Saponins from Common Selfheal(Prunella vulgaris) On Experimental Myocardial Infarction and Hypertension of Anesthetized Rats
- VernacularTitle:夏枯草总甙对麻醉大鼠急性心肌梗死的保护作用及降血压作用
- Author:
Haibo WANG
;
Zhiyu ZHANG
;
Zhongwu SU
- Publication Type:Journal Article
- From:
Chinese Traditional and Herbal Drugs
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Effects of total saponins from Prunella vulgaris (PVS)on acute myocardial infarction and hypertension of anesthetized rats were assessed. Pretreatment with PVS at a dose of 40mg/kg ip lowered Lg PVC, Lg (VT+VF) and ischemic arrhythmic scores; at a dose of 20mg/kg ip,resulted in a significant reduction of infarct size as compared with the controls; 2. 5mg/kg iv showed an hypotensive action to both systolic and diastolic blood pressure.
