CHANGES OF CALCITONIN GENE-RELATED PEPTIDE-LIKE IMMUNOREACTIVE (CGRP-LI) NERVE FIBERS OF THE ANTERIOR PITUITARY IN THE RAT AFTER ADRENALECTOMY
- VernacularTitle:肾上腺切除后大鼠垂体前叶降钙素基因相关肽免疫反应神经纤维的变化
- Author:
Dan MA
;
Gong JU
;
Sichang FAN
- Publication Type:Journal Article
- Keywords:
Adrenalectomy;
CGRP;
Anterior pituitary;
Immunohistochemistry;
Rat
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Using immunohistochemical method in the present study we examined the changes of the CGRP-LI nerve fibers in the anterior pituitary (AP) of the rat after adrenalectomy. 60 male adult rats were divided into 5 groups at random, i.e., normal, sham-operated, adrenalectomized (AdX) plus hydrocortisone, normal plus hydrocortisone and AdX groups. There were some of CGRP-LI nerve fibers sparsely and unevenly distributed in the normal rat AP. The fibers which had some varicosities and varied in their thickness could occurred either individually or in plexus. The quantity of CGRP-LI nerve fibers increased in number, length, branches and the density of the varicosities. The extent of their distribution was also enlarged. With a Leitz computer-assisted image analyzer the quantity of the CGRP-LI nerve fibers in the 5 groups was measured and the results showed that the amount of CGRP-LI nerve fibers in AdX group was significantly higher than those in all the other groups (P
