THE ORIGIN OF THE CCK-IMMUNOREACTIVE NERVE FIBERS IN THE POSTERIOR PITUITARY OF THE RAT
- VernacularTitle:大鼠垂体后叶胆囊收缩素能神经纤维的起源
- Author:
Shaojun LIU
;
Gong JU
- Publication Type:Journal Article
- Keywords:
CCK;
Immunohistochemistry;
Retrograde tracing;
Posterior pituitary;
Rat
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The WGA-HRP retrograde tracing combined with immunohistochemical method was used to study the sources of CCK positive fibers in the male rat posterior pituitary. The CCK positive neurons projecting to the posterior pituitary localized mainly in the paraventricular nucleus, periventricular areas,and medial preoptic area. A few double labeled neurons were demonstrated in the subependymal area of the interventricular foramen and the floor of the 3rd ventricle. The CCK positive neurons projecting to the posterior pituitary, which weakly stained, were found in the bed nucleus of the stria terminalis, lateral hypothalamic area and the dorsal part of the supraoptic nucleus, too. Our result showed much more distribution of CCK-ir neurons projecting to the posterior pituitary in the hypothalamus than Palkovits′conclusion that the CCK positive fibers in posterior pituitary almost all originated from the magnocellular paraventricular nuclei. Some double labeled neurons in periventricular area were closely approximte to 3rd venticular cavity which suggested that these neurons may monitor the changes in the cerebrospinal fluid.
