EFFECT OF RACEMIC (?) GOSSYPOL AND TOTAL GLYCOSIDES FROM TRIPTERYGIUM WILFORDII(GTW) ON HUMAN SPERM ACROSOME REACTION IN VITRO
- VernacularTitle:消旋棉酚和雷公藤总甙对体外人精子顶体反应的影响
- Author:
Zhiqiang HAN
;
Guorong ZHANG
;
Shixiao LI
;
Bailian DU
- Publication Type:Journal Article
- Keywords:
Acrosome reaction;
Gossypol;
Glycosides of tripterygium wilfordii;
Human sperm
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The effect of racemic(?) gossypol and total glycosides of tripterygium wilfordii (GTW) on human sperm acrosome reaction was observed by indirect immunofluorescence and transmission electron microscopy. The results indicate that recemic (?) gossypol and GTW may significantly inhibit human sperm acrosome reaction induced by ionophore A_(23187) at 5mg/L and 10mg/L respectively. The results of TEM shows that racemic (?) gossypol and GTW may injure the sperm plasma membrane.
