ELECTRON MICROSCOPIC STUDY OF THE CHANGES OF CONNECTIVE TISSUE CELLS DURING THE SKIN WOUND HEALING IN RATS
- VernacularTitle:大鼠皮肤创伤愈合过程中结缔组织细胞变化的电镜研究
- Author:
Zhounan WANG
;
Binghua ZHAO
;
Guang LI
;
Yuanhong JIANG
- Publication Type:Journal Article
- Keywords:
Skin wound healing;
Fibroblast;
Myofibroblast;
Fibroclast;
Mast cell;
Rat
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Open skin wounds were made in 28 Wistar rats, and the changes of the connective tissue cells were observed by electron microscopy during wound healing. The fibroblasts and macrophages were increased in the early stage, later on the fibroblasts might be transformed into myofibroblasts which became preponderant cells in the wound gradually and led to wound contraction and scar formation. The intercellular substances were phagocytosed by fibroclasts simultaneously. The mast cells were closely apposed to the fibroblasts or myofibroblasts and represented active functions, such as degranulation. Considerably they released the granule contents to the extracellular space and effected the other cells functions. It shows that the cells mentioned above interplay and take part in the wound healing.
