HISTOLOGICAL AND HISTOCHEMICAL CHANGES OF THYMIC NURSE CELLS AND IMMUNE ORGANS OF MOUSE AFTER THE INOCULATION OF LEUKEMIC CELLS
- VernacularTitle:接种白血病细胞后小鼠胸腺哺育细胞和免疫器官组织学及组织化学的变化
- Author:
Jianmin XING
;
Jiwu MIAO
;
Shufen XU
;
Lanzhen YIN
;
Dahui QIN
;
Yan LI
- Publication Type:Journal Article
- Keywords:
Thymus;
Thymic nurse cell (TNC);
Lymph node;
Cytochemistry;
P_(388) leukemic mice
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
It was discovered in this experiment that 3 days after inoculation of the ascitic fluid from P_(388) leukemic mice, the positive percentages of AcP and ?-Gase of the lymphocytes within the TNC of the recipients were increased significantly, while the positive percentage of ANAE was decreased. All the positive percentages of the three enzymes of the thymocytes within the thymus were increased significantly, but no abnormal structural changes were seen in the thymus. No histological and cytochemical changes were found in the lymph nodes and the spleen. Nine days after inoculation, the leukemia cell infiltration, hemorrhage and cell degeneration occurred in all the thymus, lymph nodes and spleen of the mouse. The normal structures of the organs were destroyed. The positive percentages of the cytochemical reactions of the three enzymes in the lymphocytes were all increased significantly. At this stage, TNC was very difficult to be isolated from the thymus. The results indicate that thymus and TNC may have a close relationship with the development of this type of leukemia.
