THE ELECTRON MICROSCOPIC STUDY OF THE PERIVENTRICULAR OXYTOCIN IMMUNOREACTIVE NEURONS OF THE THIRD VENTRICLE IN THE RAT
- VernacularTitle:大鼠第三脑室周围催产素样免疫反应神经元的免疫电镜研究
- Author:
Hong YANG
;
Gong JU
- Publication Type:Journal Article
- Keywords:
Oxytocin;
Periventricular area;
Immunoelectron microscope;
Rat
- From:
Acta Anatomica Sinica
1954;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The periventricular oxytocin(OXT)-immunoreactive neurons of the 3 third ventricle in the rat were studied under electron microscope by using pre-embedding PAP immunocytochemistry. Special attention was payed to the relationship between OXT-containing neurons and ependymal cells and the synaptic architecture of these neurons in the periventricular neuropil. The results revealed that the positively immunostained cell bodies and larger, dendrites of neurons were just beneath ependyma and contacted directly with ependymal cells. Typical Gray Ⅰ type or untypical axon-dendrite synapses were found between the immunolabelled neurons and unlabelled axon terminals. A cross section of a immunoreactive process was seen on the luminal surface of ependymal cells in one case. In the subependymal neuropil many synapses formed by OXT-immunoreactive dendrites and non-immunoreactive axon terminals which contained different kinds of synaptic vesicles were encountered. It is suggested that the subependymal neurons may be important in signal integation between cerebrospinal fluid and neuronal inputs. It is also possible that the subependymal neurons may release peptides,i, e. oxytocin into CSF.
