THE SECRETING MANNER OF THE ATRIAL MYOENDOCRINE CELLS AND THE RELATIONSHIP BETWEEN THE ATRIAL MYOENDOCRINE CELLS AND THE NERVES AND CAPILLARIES——AN ELECTRON MICROSCOPE STUDY
- VernacularTitle:心房内分泌肌细胞的分泌方式及其与神经、毛细血管关系的超微结构研究
- Author:
Ping YAN
;
Jianben WANG
- Publication Type:Journal Article
- Keywords:
Atrial myoendocrine cells;
Atrial natriuretic factor(ANE);
Exocytosis;
Ultrastructure;
Rat
- From:Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The ultrastructural changes of atrial myoendocrine cells (AMC) in various volume loading for heart, the type and the distribution of nerve endings and capillaries in the vicinity of AMC were observed with electron microscopy. The rats deprived or undeprived water received an injection of isotonic saline via the femoral vein (20 ml/mg), then the right auricle was removed and fixed with usual method for EM and partly with TAGO method. The process of atrial specific granules (ASG) secretion, i. e., the limiting membrane of ASG fused with the sarcolemma and opened at this place, and the ASG content was released through this opening into extracellular space, were observed. There were various types of nerve endings nearby AMC. The capillaries were continuous endothelium in type, and show close relation to AMC. The results of this study suggest that AMC secrete ANF by exocytosis mainly, and provide some morphologic data for the physiological and biochemical studies of ANF move and of reaction on each other between the ANF and nerves.
