A QUANTITATIVE INVESTIGATION ON SYNAPTIC STRUCTURAL PLASTICITY IN THE BRAIN OF MICE TREATED WITH DGAVP
- VernacularTitle:脱甘氨酰胺精氨酸加压素引起小鼠脑内突触结构可塑性变化的定量观察
- Author:
Lan LUO
;
Hanxin LU
;
Fumei WU
;
Xinsheng XIAO
- Publication Type:Journal Article
- Keywords:
CA_3 area of hippocampus;
Sensori-motor area of of cortex;
Synaptic plasticity;
Learning and memory;
Desglycinamide-arginine-8-vasopressin (DGAVP);
Electron microscopy;
Mice
- From:
Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
The changes of some parameters of Gray type Ⅰ synaptic interface in the brain of mice treated with desglycinamide-arginine-8-vasopressin (DGAVP) have been analysed quantitatively two hours after DGAVP injection. The animals were killed and the hippocampus and sensori-motor area of cerebral cortex were prepared for electron microscopy. The electron microphotographs were analysed by IBM-PC computer image processing system. The main results of the experiment are as follows:1. The thickness of postsynaptic density apparently increased in both the sensori-motor area of cerebral cortex and CA_3 area of hippocampus after injection of DGAVP (P
