AN EXPERIMENTAL STUDY OF LIVINGBCG'S EFFECT ON THE KILLING AND DIGESTIVE ABILITIES OF RABBIT ALVEOLAR MACROPHAGE LYSOSOME TO LIVING-YEAST
- VernacularTitle:活卡介苗对家兔肺泡巨噬细胞溶酶体杀伤和消化酵母菌的实验研究
- Author:
Qiang ZHAO
;
Ming YU
- Publication Type:Journal Article
- Keywords:
Alveolar macrophage;
Endocytosis;
Acridine orange;
BCG;
Fluorescence microscope
- From:Acta Anatomica Sinica
1953;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
By means of the observation of acridine orange-stained lysosomes with fluorescence microscope, we studied the intracellular killing and digestive process after alveolar macrophage (AM) ingested living-yeast. Based on the morphological changes of the cells, we divided the process into three stages: the pre-phagosome-lysosome fusion stage, the phagosome-lysosome fusion and killing stage, and the digestive stage. The results revealed that all the values of phagocytic index, phagocytic rate, fusion index and fusion rate of the isolated AM of rabbits infected with living-BCG were higher than those of normal rabbits (P
