AN IMMUNOHISTOCHEMICAL STUDY OF SUPRAEPENDYMAL SEROTONINERGIC NERVE FIBERS IN THE RAT FOREBRAIN
- VernacularTitle:大鼠前脑室管膜上5-羟色胺能神经纤维的免疫组织化学研究
- Author:
Xia ZHANG
;
Gong JU
;
Xiaoqin DUAN
- Publication Type:Journal Article
- Keywords:
Serotonin;
Supraependymal nerve fibers;
Immunohistochemistry
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
A sensitive ABC or PAP immunohistochemical technique visualized with glucose oxidase-DAB-nickel method was used to examine the distribution and characteristics of the supraependymal serotoninergic nerve fibers (5-HT-SEP) in the adult rat forebrain. Three types of fibers could be distinguished: a few thick fibers (about 0.9?m in diameter), large amount of intermediate fibers (about 0.4?m in diameter), and numerous thin fibers (about 0.1?m in diameter). Although the 5-HT-SEP were found in all areas of the forebrain ependyma, the density and distribution patterns of different fiber types varied. In addition, the correspondence between the densities of ependymal cilia and 5-HT-SEP indicates the modulation of the cilia activity by 5-HT-SEP.