OBSERVATION OF SEXUAL DIMORPHISM OF SOMATOSTATIN IMMUNOREACTIVE NEURONS IN THE RAT HYPOTHALAMUS
- VernacularTitle:大鼠下丘脑生长抑素神经元性差别的观察
- Author:
Ying QIN
;
Guozhen QIAN
- Publication Type:Journal Article
- Keywords:
Hypothalamus;
Somatostatin neurons;
Sexual dimorphism
- From:
Acta Anatomica Sinica
1957;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The distribution and numbers of SRIF-immunoreactive cell bodies and fibers in normal and castrated rats hypothalamus were studied by PAP immunocytochemistry. The results showed that the positive cell bodies and fibers in periventricular nucleus (PV), suprachiasmatic nucleus (SCN) and paraventricular nucleus (PVN) were more numerous in male than in female. Another marked sexual dimorphism was found in medial preoptic area (MPO) which was filled with dense plexus of varicose immunoreactive fibers in male, while there were low density of stained fibers in female. Orchiectomized rats had fewer number of positive neurons in PV, PVN, SCN and arcuate nucleus (ARN), and lower density of fiber in SCN, ARN, MPO and median eminence than the normal rats. On the contrary, in the ovariectomized rats could find more numerous cell bodies and fibers in these areas. When gonadal steroid was given after gonadectomy, the SRIF neurons became similar to the normal.
