APPLICATION OF LINEAR REGRESSION METHOD OF MULTIWAVELENGTH DATA AND ORTHOGONAL FUNCTIONS SPECTROPHOTOMETRY——DETERMINATION OF SULFAMETHOXAZOLE AND TRIEMETHOPRIM IN CO-TRIMOXAZOLE TABLETS
- VernacularTitle:多波长数据线性回归法和正交函数分光光度法的应用——复方新诺明片的测定
- Author:
Jingchuan SHANG
;
Yu OUYANG
- Publication Type:Journal Article
- Keywords:
Linear regression method;
Orthogonal functions method;
co-trimoxazole tablets;
Sulfamethoxzole;
Triemethoprim
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
The linear regression method of multiwavelength data and orthogonal functions spectropho-tomtry have been used for the determination of sulfamethoxazole and triemethoprim in co-trimo-xazole tablets without any preliminary separation.The methods are simple and rapid.Good results have been obtained. The average recovery of sulfamethoxazole was 99.72-100.5%, with coefficient of variation below 0.48%, and the average recovery of triemethoprim was 99.26-99.46%, with coefficient of variation below 0.83%. The accuracy and precision meet the requirements of analysis of the pharmaceutical preparations
