Clinical Factors Associated with Hepatitis A Virus Seropositivity in HIV-Infected Adults Living in a Country with an Epidemiologic Shift for Hepatitis A Virus Infection.
10.3346/jkms.2012.27.8.969
- Author:
Ji Hyeon BAEK
1
;
Chang Oh KIM
;
Jun Yong PARK
;
Su Jin JEONG
;
Nam Soo KOO
;
Hye Won KIM
;
Sang Hoon HAN
;
Jun Yong CHOI
;
Young Goo SONG
;
June Myung KIM
Author Information
1. Department of Infectious Disease, Inha University Hospital, Incheon, Korea.
- Publication Type:Brief Communication
- Keywords:
HIV;
HAV;
Seropositivity
- MeSH:
Adult;
Age Factors;
CD4 Lymphocyte Count;
Female;
HIV Infections/*complications;
Hepatitis A/complications/*epidemiology;
Hepatitis A Antibodies/blood;
Hepatitis A virus/immunology;
Humans;
Male;
Middle Aged;
Odds Ratio;
Republic of Korea/epidemiology;
Seroepidemiologic Studies
- From:Journal of Korean Medical Science
2012;27(8):969-971
- CountryRepublic of Korea
- Language:English
-
Abstract:
The number of HIV-infected individuals susceptible to Hepatitis A virus (HAV) infection is increasing in Korea; however, it has proven difficult to devise a vaccination policy therefore because limited seroepidemiologic data exists for them. Accordingly, anti-HAV IgG was measured in 188 HIV-infected adults between July 2008 and July 2010. The nadir CD4+ T lymphocyte counts were not different between the HAV-positive and -negative groups (197 +/- 138 vs 202 +/- 129, P = 0.821). The only factor independently associated with seropositive status was age under 40 yr old (OR 0.017, P < 0.001). Our findings suggest that HAV vaccination in HIV-infected adults should be targeted at persons under the age of 40 yr.
