HEMOSTATIC PROBLEMS AND ENDOTOXEMIA IN LIVER DISEASE
- VernacularTitle:肝脏疾病疑血功能障碍与内毒素血症
- Author:
Lelee DAI
;
Baoyuan XU
- Publication Type:Journal Article
- Keywords:
Endotoxemia;
Limulus Lysate assay;
Clotting abnormalities;
Fibro-nectin;
Hepaplastion test
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Plasma Limulus Lysate assay, fibronectin, blood coagulation picture (Fbg, FⅡ, HPT, PT, ⅧR:Ag) and antithrombin-Ⅲ were determined in G1 patients with liver disease. The frequency of endotoxemia depended upon the degree and extent of hepatic injury and the phagocytic activity of the Kupffer cells. The coagulation abnormalities were multifactorial, there were not only the changes of clotting proteins, but also the diminution of antithrombin-Ⅲ. Multivariate analysis showed that the frequency of endotoxemia was closely correlated with the changes of fibronectin, clotting proteins and antithrombin-III (P
